Projectes
El proyecto DeNaPol aprovecha una nueva clase de enzimas con múltiples sitios reactivos, las pluriZimas, y las rediseñará para la degradación eficiente de micropartículas y nanopartículas plásticas y textiles. Se enfrenta así a un problema social muy importante, ayudando en el tratamiento de eliminación de...
Pancreatic ductal adenocarcinoma (PDAC) prognosis has not significantly improved during the past thirty years due to the lack of efficacious treatments. Chemotherapy-based treatments such as Gemcitabine/Nab-Paclitaxel or Folfirinox remain the current options for PDAC patients with an overall five-year survival below 10%. Importantly, PDAC cases are increasing and expected to...
The aim of the BOREAS project is to blend knowledge from climate predictions and projections to make the Spanish energy sector more resilient to climate variability and climate change, hence contributing to the better management of the current climate and energy crises.
Spain has the objective to reach climate neutrality by 2050, which is part of the...
The goal of HEAVY is to better understand and quantify the emission, transport and deposition of coarse and super coarse dust and their role on dust climate effects.
The overarching hypotheses are that 1) coarse and super coarse dust play a fundamental role in shaping the overall climate effect of desert dust, 2) a combination of uncertainties and...
Hi ha un consens compartit en el sector agrícola sobre la importància que tindrà l'agricultura de precisió con a eina imprescindible per la millora de la productivitat. L´agricultura de precisió es basa en d'eines d'anàlisis computacionals per optimitzar l'ús de recursos agrícoles, aplicant-los en aquelles parts d...
El corazón es principalmente una bomba altamente especializada que sustenta la vida proporcionando suficiente flujo de sangre a todo el cuerpo. Como tal, comprender la función completa del corazón en la salud y la enfermedad es de primordial importancia para el avance de dispositivos médicos, medicamentos y terapias. Los avances en el modelado...
The deposition of dust and other terrestrial aerosols represents an external supply of nutrients to the ocean surface. This supply helps sustain...
Aerosols constitute an important component in the physics and chemistry of the atmosphere, and concretely of the atmospheric radiative balance and cloud formation, and yet the uncertainties about aerosols concentrations and distributions, and about their life cycle are considerable.
The recent advances in numerical modeling developments, observational...
Microbial production of plant metabolites has economic & environmental benefits over traditional extraction and chemical methods. Despite initial progress & the successful market introduction of some molecules, the microbial production of oxygenated plant metabolites (OPMs) mediated by cytochrome P450 enzymes (CYPs) is still lagging, making them almost inaccessible to...
The main objective of this proposal is to develop new tools based on artificial intelligence to find active molecules capable of antagonizing protein-protein contacts or acting as molecular glues of proteins of pharmacological interest, in particular targets for immune-mediated inflammatory skin conditions.
Proyecto CPP2022-009737 financiado por...