Toni Gabaldon

The comparative genomics group (www.cgenomics.org ) is jointly affiliated to the Barcelona Supercomputing Centre (BSC) and the Biomedical Research Institute (IRB).

The main research interest of our group is to understand the complex relationships between genome sequences and phenotypes and how these two features evolve within and across species. We...

The origin of eukaryotes has been defined as the major...

The traditional view is that species and their genomes evolve only by vertical descent, leading to evolutionary histories that can be represented by bifurcating lineages. However, modern evolutionary thinking recognizes processes of reticulate evolution, such as horizontal gene transfer or hybridization, which involve total or partial...

Long non-coding RNAs (lncRNAs) are abundant in mammalian transcriptomes. However, it remains unclear how many of them are functional, and how their functions are performed. LncRNAs seem to be poorly conserved at the sequence level, but some of them share conserved structural elements and are present at syntenic genomic positions in different species.

A...