Marta Mele

This project aims to uncover molecular processes in postnatal development as well as genetic and nongenetic sources of inter-individual molecular variation, with the ultimate goal of better understanding human biology and disease. We will achieve these goals by developing novel and innovative analysis methods and approaches applied to multimodal Developmental GTEx data types...

Comprender las consecuencias de la variación en la expresión génica es fundamental para descifrar la biología y las enfermedades humanas. Los análisis a gran escala de la expresión génica han revolucionado nuestra comprensión de una miríada de procesos biológicos, permitiéndonos conectar cambios...

The Transcriptomics and Functional Genomics Lab, led by Marta Melé, is interested in understanding how the information encoded in our genome determines gene expression and splicing variation across individuals and tissues. To address this, we use a combination of cutting-edge computational analyses, next generation sequencing, and high-throughput functional...

This project provides a unique opportunity to distinguish how genetics and environment impact gene expression and immune response among people of African ancestry, increasing the understanding of variable risk for both communicable and non-communicable diseases. There are currently only a few available single cell reference biological data of tissues from pediatric healthy...