SHDC - Sex differences in Human Diseases and Comorbidities

Software that analyzes gene expression data available in public databases such as GEO and ArrayExpress to study similarities between diseases by analyzing women and men separately. This software identifies first the sex of the samples based on the expression levels of genes on the Y chromosome, and then performs data normalization, differential expression, functional enrichment and study of similarities between diseases based on the differential expression profiles and the enriched biological processes. Software results are in turn made available for use by the scientific community.