Projects

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The central objective of FOCUS-Africa is to develop sustainable tailored climate services in the Southern African Development Community (SADC) region for four sectors:

  • agriculture and food security
  • water
  • energy
  • infrastructure

The proposed co-production amongst end-users, climate scientists and sectoral service providers will ensure...

Roughly 30% of Nationally Determined Contributions (NDCs) under the Paris Agreement (PA) include land-based mitigation measures, but there are still significant uncertainties in their effectiveness to deliver negative emissions. Aside from the expected shortfall of all current NDCs to deliver on the below 2 oC ambition, this uncertainty adds to the risks to human wellbeing as...

At the time of writing of this proposal, most European countries have imposed lockdowns to combat the spread of the COVID-19 pandemic, which have forced many industries, businesses and transport networks to either close down or drastically reduce their activity. Such economic interruption, which is unprecedented in many ways, is resulting in a sudden drop of atmospheric...

Modeling the heartbeat is a highly complex task that involves several scales and different tightly coupled problems. A large number of spatial orders of magnitude are linked, from the microscopic cell arrangement into a volumetric description, to the macroscopic shape of the cardiac chambers. In the same way, several temporal scales coexist, from...

Due to technological advances in experimental biology, we now have an astounding amount of various molecular and clinical data describing different aspects of the functioning of the cells. These complex big data carry biomedical information that is currently hidden from us within their large sizes and complexities. Hence, some of the foremost computational challenges that the...

Over the last decade we have made significant progress in understanding the role of genetics in cancer predisposition, evolution andtreatment. We now have thousands of germline variants associated with different types of cancer and we have also identified a fewhundred genes that, when somatically mutated, drive the growth of cancer cells.However, there are also many open...

Gene expression determines the identity of cells and thus, it governs the process by which organs and tissues are formed and organized inan individual. Furthermore, differences in gene expression between individuals are known to play a crucial role in determining disease risk. However, the mechanisms of how such differences in gene expression are associated with disease...

Air quality modelling, urban mobility actions, multi-scale, health impact Air pollution continues to be one of the main issues in urban areas. In the particular case of Barcelona (Spain), chronic NO2 and PM2.5 exceedances are still recorded in urban traffic stations, highlighting the contribution of the road transport sector to population exposure to ambient concentrations....

Mesopelagic ocean, biogeochemistry, climate, carbon, plankton, particles, respiration, advection, model, Argo The mesopelagic layer of the oceans, also known as the Twilight Zone, extends between ~200 and 1000 m depth and is one of the vastest contiguous ecosystems on Earth. It plays a pivotal role in global biogeochemical cycles and climate, and hosts a massive biomass of...

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