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Mostrando 11 - 20 resultados de 124

2024

Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection

Nature Communications

C. Ávila-Nieto, J. Vergara-Alert, P. Amengual-Rigo, E. Ainsua-Enrich, M. Brustolin, M. Luisa Rodr de la Concepción, N. Pedreño-Lopez, J. Rodon, V. Urrea, E. Pradenas, S. Marfil, E. Ballana, E. Riveira-Muñoz, M. Pérez, N. Roca, F. Tarrés-Freixas, G. Cantero, A. Pons-Grífols, C. Rovirosa, C. Aguilar-Gurrieri, R. Ortiz, A. Barajas, B. Trinité, R. Lepore, J. Muñoz-Basagoiti, D. Perez-Zsolt, N. Izquierdo-Useros, A. Valencia, J. Blanco, V. Guallar, B. Clotet, J. Segalés, and J. Carrillo
Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches

Frontiers in Immunology

A. Niarakis, M. Ostaszewski, A. Mazein, I. Kuperstein, M. Kutmon, M. E. Gillespie, A. Funahashi, M. Luis Acencio, A. Hemedan, M. Aichem, K. Klein, T. Czauderna, F. Burtscher, T. G. Yamada, Y. Hiki, N. F. Hiroi, F. Hu, N. Pham, F. Ehrhart, E. L. Willighagen, A. Valdeolivas, A. Dugourd, F. Messina, M. Esteban-Medina, M. Peña-Chilet, K. Rian, S. Soliman, S. Sadat Aghamiri, B. Lal Puniya, A. Naldi, T. Helikar, V. Singh, M. Fariñas Fernández, V. Bermudez, E. Tsirvouli, A. Montagud, V. Noël, M. Ponce-de-Leon, D. Maier, A. Bauch, B. M. Gyori, J. A. Bachman, A. Luna, J. Piñero, L. I. Furlong, I. Balaur, A. Rougny, Y. Jarosz, R. W. Overall, R. Phair, L. Perfetto, L. Matthews, D. Arokia Bal Rex, M. Orlic-Milacic, L. Cristobal Gomez, B. De Meulder, J. Marie Ravel, B. Jassal, V. Satagopam, G. Wu, M. Golebiewski, P. Gawron, L. Calzone, J. S. Beckmann, C. T. Evelo, P. D’Eustachio, F. Schreiber, J. Saez-Rodriguez, J. Dopazo, M. Kuiper, A. Valencia, O. Wolkenhauer, H. Kitano, E. Barillot, C. Auffray, R. Balling, and R. Schneider
Roadmap for a European cancer data management and precision medicine infrastructure

Nature Cancer

M. Nikolski, E. Hovig, F. Al-Shahrour, N. Blomberg, S. Scollen, A. Valencia, and G. Saunders
UNCAN.eu: Toward a European Federated Cancer Research Data Hub

Cancer Discovery

M. Boutros, M. Baumann, A. Bigas, L. Chaabane, J. Guérin, J. K. Habermann, A. Jobard, P G. Pelicci, O. Stegle, G. Tonon, A. Valencia, E. C. Winkler, P. Blanc, R. De Maria, R. H. Medema, P. Nagy, J. Tabernero, and E. Solary
Virus-like particle-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice

Journal of Translational Medicine

A. Barajas, P. Amengual-Rigo, A. Pons-Grífols, R. Ortiz, O. Gracia Carmona, V. Urrea, N. de la Iglesia, J. Blanco-Heredia, C. Anjos-Souza, I. Varela, B. Trinité, F. Tarrés-Freixas, C. Rovirosa, R. Lepore, M. Vazquez, L. De Mattos-Arruda, A. Valencia, B. Clotet, C. Aguilar-Gurrieri, V. Guallar, J. Carrillo, and J. Blanco
Lung Tissue Multi-Layer Network Analysis Uncovers the Molecular Heterogeneity of COPD

Am J Respir Crit Care Med .

N. Olvera, J. Sánchez-Valle, I. Núñez-Carpintero, J. Rojas-Quintero, G. Noell, S. Casas-Recasens, A. Faiz, P. Hansbro, A. Guirao, R. Lepore, D. Cirillo, A. Agustí, F. Polverino, A. Valencia, and R. Faner
Frustraevo: a web server to localize and quantify the conservation of local energetic frustration in protein familiesAbstract

Nucleic Acids Research

G. R. Parra, M. I. Freiberger, M. Poley-Gil, M. Fernandez-Martin, L. G. Radusky, V. Ruiz-Serra, P. G. Wolynes, D. U. Ferreiro, and A. Valencia
Rare disease research workflow using multilayer networks elucidates the molecular determinants of severity in Congenital Myasthenic Syndromes

Nature Communications

I. Núñez-Carpintero, M. Rigau, M. Bosio, E. O'Connor, S. Spendiff, Y. Azuma, A. Topf, R. Thompson, T. Chamova, I. Tournev, V. Guergueltcheva, S. Laurie, S. Beltran, S. Capella-Gutierrez, D. Cirillo, H. Lochmüller, and A. Valencia

2023

Local energetic frustration conservation in protein families and superfamilies

Nature Communications

M. I. Freiberger, V. Ruiz-Serra, C. Pontes, M. Romero-Durana, P. Galaz-Davison, C. A. Ramírez-Sarmiento, C. D. Schuster, M. A. Marti, P. G. Wolynes, D. U. Ferreiro, G. R. Parra, and A. Valencia
Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant

Frontiers in Immunology

C. Ávila-Nieto, J. Vergara-Alert, P. Amengual-Rigo, E. Ainsua-Enrich, M. Brustolin, M. Luisa Rodr de la Concepción, N. Pedreño-Lopez, J. Rodon, V. Urrea, E. Pradenas, S. Marfil, E. Ballana, E. Riveira-Muñoz, M. Pérez, N. Roca, F. Tarrés-Freixas, J. Carabelli, G. Cantero, A. Pons-Grífols, C. Rovirosa, C. Aguilar-Gurrieri, R. Ortiz, A. Barajas, B. Trinité, R. Lepore, J. Muñoz-Basagoiti, D. Perez-Zsolt, N. Izquierdo-Useros, A. Valencia, J. Blanco, B. Clotet, V. Guallar, J. Segalés, and J. Carrillo

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